How Your Body Processes Medications

By Paul Henry / in , , , , , , , /

(bright music) – [Narrator] How our body
breaks down pharmaceuticals can mean the difference
between treatment success, or failure, or something worse. Pharmacokinetics is the term
used to describe the four stages of how medications
move through your body. After we take a drug, it enters our bloodstream. That’s the first stage
known as absorption. The route by which we take
drugs affect how quickly they’ll enter our bloodstream. Following absorption, the
drug is carried throughout the body in the bloodstream in a process known as distribution. This is when the medication
reaches its target site such as fat, muscle, or brain tissue. The third stage, metabolism,
is when drugs are chemically altered, or metabolized, by your body. All tissues in your body are responsible for drug metabolism, but most of the work
is done by your liver. That’s because your liver
contains the largest concentration of metabolic enzymes
and these enzymes help to break down medications. 70 to 80% of the enzymes
involved in drug metabolism are found in the cytochrome
P450 group of genes. The rate at which your
body metabolizes drugs determines how much of
the drug is available. If your body metabolizes
a drug too slowly, it stays active longer and as a result, you may experience side effects. If your body metabolizes
a drug too quickly, the drug may not have a
chance to reach blood levels high enough to provide benefit. Depending on your drug metabolism rate, you may need more or less
of a certain medication. Excretion is the last stage. Our body gets rid of most
drugs through our urine, but also through our sweat, saliva, feces, breast milk, or exhalation. Several factors affect how
quickly your body can absorb, distribute, metabolize, and excrete drugs. Understanding how each
person processes drugs can help doctors prescribe
the right medication at the right dose and even save lives. Genetic testing can help
give your doctor insight into your ability to
metabolize certain drugs based on your CYP genes. More than 260 medications have
pharmacogenomic bio markers on their labels and that
is why it is important for you to carry your Genomind
Rx MetaType Card with you. It can help inform doctors what
type of metabolizer you are. Ask your doctor for the
Genomind Professional PGx Express Test today. Visit
for more information.

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